Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including NEDD8 ligase activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and ubiquitin protein ligase binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including positive regulation of intracellular signal transduction; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein modification by small protein conjugation. Predicted to be located in nucleoplasm. Predicted to be part of cullin-RING ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human RBX1 (ring-box 1).