Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables identical protein binding activity and mechanosensitive cation channel activity. Involved in cation transport and positive regulation of myotube differentiation. Acts upstream of or within cation transmembrane transport; detection of mechanical stimulus; and regulation of membrane potential. Located in plasma membrane. Is expressed in several structures, including hemolymphoid system; liver; and lung. Human ortholog(s) of this gene implicated in dehydrated hereditary stomatocytosis 1 and hereditary lymphedema. Orthologous to human PIEZO1 (piezo type mechanosensitive ion channel component 1).