Automated description from the Alliance of Genome Resources (Release 7.0.0)
Acts upstream of or within determination of left/right symmetry and heart development. Is active in cytosol. Is expressed in several structures, including brain; nasal cavity respiratory epithelium; and respiratory system epithelium. Used to study Kartagener syndrome; primary ciliary dyskinesia 21; and visceral heterotaxy. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 21 and spermatogenic failure. Orthologous to human DRC1 (dynein regulatory complex subunit 1).