Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in chromatin organization; in utero embryonic development; and oocyte growth. Predicted to localize to MLL3/4 complex. Is expressed in several structures, including central nervous system; face; integumental system; sensory organ; and vault of skull. Used to study Kabuki syndrome. Human ortholog(s) of this gene implicated in Kabuki syndrome and esophagus squamous cell carcinoma. Orthologous to human KMT2D (lysine methyltransferase 2D).