Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in brain development and positive regulation of neuroblast proliferation. Acts upstream of or within several processes, including in utero embryonic development; nervous system development; and regulation of histone H3-K4 methylation. Located in nucleus. Part of histone methyltransferase complex. Is expressed in brain and future brain. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 10. Orthologous to human ZNF335 (zinc finger protein 335).