Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables fructose-2,6-bisphosphate 2-phosphatase activity. Involved in positive regulation of pentose-phosphate shunt and response to ischemia. Acts upstream of or within several processes, including fructose 2,6-bisphosphate metabolic process; negative regulation of catabolic process; and positive regulation of cardiac muscle cell apoptotic process. Located in mitochondrion. Is expressed in several structures, including brain; immune system; and liver. Orthologous to human TIGAR (TP53 induced glycolysis regulatory phosphatase).