GO Annotations Graph

• Symbol: Tigar
• Name: Trp53 induced glycolysis regulatory phosphatase
• ID: MGI:2442752

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity	ISO	J:164563
Molecular Function	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity	IBA	J:265628
Molecular Function	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity	IMP	J:167245
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:211335
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:211335
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0006914	autophagy	IEA	J:60000
Biological Process	GO:0010659	cardiac muscle cell apoptotic process	IMP	J:183674
Biological Process	GO:0010659	cardiac muscle cell apoptotic process	IMP	J:183674
Biological Process	GO:0071279	cellular response to cobalt ion	ISO	J:164563
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0030388	fructose 1,6-bisphosphate metabolic process	ISO	J:164563
Biological Process	GO:0030388	fructose 1,6-bisphosphate metabolic process	IBA	J:265628
Biological Process	GO:0006003	fructose 2,6-bisphosphate metabolic process	ISO	J:164563
Biological Process	GO:0006003	fructose 2,6-bisphosphate metabolic process	IBA	J:265628
Biological Process	GO:0006003	fructose 2,6-bisphosphate metabolic process	IMP	J:167245
Biological Process	GO:0019661	glucose catabolic process to lactate via pyruvate	IMP	J:167245
Biological Process	GO:0006096	glycolytic process	IDA	J:167245
Biological Process	GO:0060576	intestinal epithelial cell development	IMP	J:198650
Biological Process	GO:0000423	mitophagy	IMP	J:183674
Biological Process	GO:1904024	negative regulation of glucose catabolic process to lactate via pyruvate	IMP	J:167245
Biological Process	GO:0045820	negative regulation of glycolytic process	IBA	J:265628
Biological Process	GO:0045820	negative regulation of glycolytic process	IDA	J:167245
Biological Process	GO:0033673	negative regulation of kinase activity	IC	J:167245
Biological Process	GO:1901525	negative regulation of mitophagy	IMP	J:183674
Biological Process	GO:1901215	negative regulation of neuron death	IDA	J:211335
Biological Process	GO:0043069	negative regulation of programmed cell death	ISO	J:164563
Biological Process	GO:0043069	negative regulation of programmed cell death	IBA	J:265628
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	IMP	J:183674
Biological Process	GO:0010666	positive regulation of cardiac muscle cell apoptotic process	IMP	J:183674
Biological Process	GO:0045739	positive regulation of DNA repair	ISO	J:164563
Biological Process	GO:0045739	positive regulation of DNA repair	IBA	J:265628
Biological Process	GO:1903301	positive regulation of hexokinase activity	ISO	J:164563
Biological Process	GO:0072593	reactive oxygen species metabolic process	IMP	J:183674
Biological Process	GO:0072593	reactive oxygen species metabolic process	IMP	J:183674
Biological Process	GO:0043456	regulation of pentose-phosphate shunt	ISO	J:164563
Biological Process	GO:0043456	regulation of pentose-phosphate shunt	IBA	J:265628
Biological Process	GO:1902153	regulation of response to DNA damage checkpoint signaling	ISO	J:164563
Biological Process	GO:0010332	response to gamma radiation	IMP	J:198650
Biological Process	GO:0002931	response to ischemia	IDA	J:211335
Biological Process	GO:0009410	response to xenobiotic stimulus	IMP	J:198650