Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits protein serine/threonine kinase activity. Involved in several processes, including cell surface receptor signaling pathway; lymphocyte migration into lymph node; and negative regulation of GTPase activity. Localizes to cytoplasm. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 2A; hereditary sensory neuropathy; hypertension; and pseudohypoaldosteronism. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human WNK1 (WNK lysine deficient protein kinase 1).