Automated description from the Alliance of Genome Resources
Exhibits muramyl dipeptide binding activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of cellular metabolic process; and positive regulation of cytokine production. Predicted to colocalize with the cytoplasm. Used to study inflammatory bowel disease 1. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; Blau syndrome; autoimmune hypersensitivity disease (multiple); intestinal disease (multiple); and lung disease (multiple). Orthologous to human NOD2 (nucleotide binding oligomerization domain containing 2).