Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables proton channel activity. Involved in cellular response to insulin stimulus; negative regulation of type II interferon-mediated signaling pathway; and proton transmembrane transport. Acts upstream of or within detection of gravity and inner ear morphogenesis. Located in plasma membrane. Is expressed in several structures, including adrenal gland; inner ear; integumental system; stomach; and thymus. Orthologous to human OTOP1 (otopetrin 1).