Automated description from the Alliance of Genome Resources
Predicted to contribute to pyruvate dehydrogenase (NAD+) activity. Predicted to be involved in mitochondrial acetyl-CoA biosynthetic process from pyruvate. Localizes to the mitochondrion and myelin sheath. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and respiratory system. Orthologous to human DLAT (dihydrolipoamide S-acetyltransferase).