GO Annotations Graph

• Symbol: Dlat
• Name: dihydrolipoamide S-acetyltransferase
• ID: MGI:2385311

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016407	acetyltransferase activity	IMP	J:238348
Molecular Function	GO:0016407	acetyltransferase activity	IMP	J:238348
Molecular Function	GO:0016746	acyltransferase activity	IEA	J:60000
Molecular Function	GO:0016746	acyltransferase activity	IEA	J:72247
Molecular Function	GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity	ISO	J:155856
Molecular Function	GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity	IBA	J:265628
Molecular Function	GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity	ISO	J:73065
Molecular Function	GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity	TAS	J:79566
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0034604	pyruvate dehydrogenase (NAD+) activity	ISO	J:73065
Molecular Function	GO:0034604	pyruvate dehydrogenase (NAD+) activity	ISO	J:73065
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:1902493	acetyltransferase complex	TAS	J:79566
Cellular Component	GO:0045240	dihydrolipoyl dehydrogenase complex	TAS	J:79566
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005759	mitochondrial matrix	IDA	J:45074
Cellular Component	GO:0005967	mitochondrial pyruvate dehydrogenase complex	ISO	J:164563
Cellular Component	GO:0005967	mitochondrial pyruvate dehydrogenase complex	TAS	J:79566
Cellular Component	GO:0005967	mitochondrial pyruvate dehydrogenase complex	TAS	J:79566
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0045254	pyruvate dehydrogenase complex	ISO	J:155856
Cellular Component	GO:0045254	pyruvate dehydrogenase complex	ISO	J:73065
Cellular Component	GO:0045254	pyruvate dehydrogenase complex	TAS	J:79566
Biological Process	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	ISO	J:155856
Biological Process	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	ISO	J:164563
Biological Process	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	IMP	J:123893
Biological Process	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	IMP	J:238348
Biological Process	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	IC	J:79566
Biological Process	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	ISO	J:73065
Biological Process	GO:0005975	carbohydrate metabolic process	IEA	J:60000
Biological Process	GO:0006006	glucose metabolic process	IEA	J:60000
Biological Process	GO:0006090	pyruvate metabolic process	IEA	J:72247
Biological Process	GO:0006099	tricarboxylic acid cycle	IEA	J:60000