Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including R-SMAD binding activity; enzyme binding activity; and transcription coactivator activity. Involved in several processes, including circulatory system development; positive regulation of macromolecule biosynthetic process; and regulation of signal transduction. Acts upstream of or within several processes, including circulatory system development; negative regulation of cardiac muscle cell apoptotic process; and regulation of DNA-templated transcription. Located in nucleus. Part of chromatin. Is expressed in several structures, including cardiovascular system; genitourinary system; gut; paraxial mesenchyme; and respiratory system. Used to study congenital megabladder; dilated cardiomyopathy; and patent ductus arteriosus. Human ortholog(s) of this gene implicated in congenital megabladder. Orthologous to human MYOCD (myocardin).