Automated description from the Alliance of Genome Resources
Exhibits lipoate synthase activity. Involved in several processes, including lipoate biosynthetic process; neural tube closure; and response to lipopolysaccharide. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Is expressed in alimentary system; liver; metanephros; salivary gland; and urinary system. Orthologous to human LIAS (lipoic acid synthetase).