Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits lipoate synthase activity. Involved in several processes, including lipoate biosynthetic process; neural tube closure; and response to lipopolysaccharide. Localizes to mitochondrion. Is expressed in alimentary system; liver; metanephros; salivary gland; and urinary system. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human LIAS (lipoic acid synthetase).