Automated description from the Alliance of Genome Resources
Predicted to have testosterone 16-alpha-hydroxylase activity and testosterone 6-beta-hydroxylase activity. Involved in response to bacterium. Predicted to localize to the endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in chronic myeloid leukemia; essential hypertension; precursor B lymphoblastic lymphoma/leukemia; and precursor lymphoblastic lymphoma/leukemia. Is expressed in liver and lung. Orthologous to several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A43 (cytochrome P450 family 3 subfamily A member 43); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5).