Automated description from the Alliance of Genome Resources
Predicted to have RNA polymerase II regulatory region sequence-specific DNA binding activity and protein domain specific binding activity. Involved in several processes, including chondrocyte differentiation; hair follicle development; and positive regulation of extrinsic apoptotic signaling pathway via death domain receptors. Localizes to the nucleus. Used to study trichorhinophalangeal syndrome type I. Human ortholog(s) of this gene implicated in osteochondrodysplasia; trichorhinophalangeal syndrome type I; and trichorhinophalangeal syndrome type III. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and skin. Orthologous to human TRPS1 (transcriptional repressor GATA binding 1).