Automated description from the Alliance of Genome Resources
Exhibits C2H2 zinc finger domain binding activity; histone methyltransferase activity (H3-K27 specific); and histone methyltransferase activity (H3-K9 specific). Involved in several processes, including macromolecule methylation; negative regulation of transcription by RNA polymerase II; and positive regulation of cold-induced thermogenesis. Localizes to the nucleus. Used to study Kleefstra syndrome. Human ortholog(s) of this gene implicated in Kleefstra syndrome. Is expressed in several structures, including alimentary system; forelimb; integumental system; nervous system; and respiratory system. Orthologous to human EHMT1 (euchromatic histone lysine methyltransferase 1).