Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription factor binding activity; and protein homodimerization activity. Involved in several processes, including animal organ development; anterior/posterior pattern specification; and positive regulation of cell population proliferation. Localizes to RNA polymerase II transcription repressor complex and nucleus. Is expressed in several structures, including body cavity or lining; embryo mesenchyme; genitourinary system; heart and pericardium; and vibrissa. Human ortholog(s) of this gene implicated in CAKUT2. Orthologous to human TBX18 (T-box transcription factor 18).