Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription factor binding activity; and protein dimerization activity. Involved in several processes, including animal organ development; anterior/posterior pattern specification; and positive regulation of cell population proliferation. Localizes to the nucleus. Colocalizes with the Tle3-Aes complex. Human ortholog(s) of this gene implicated in CAKUT2. Orthologous to human TBX18 (T-box 18).