Automated description from the Alliance of Genome Resources
Predicted to have I-SMAD binding activity; R-SMAD binding activity; and ubiquitin protein ligase activity. Involved in negative regulation of ossification; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization; and protein ubiquitination. Predicted to colocalize with the mitochondrion. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and respiratory system. Orthologous to human SMURF1 (SMAD specific E3 ubiquitin protein ligase 1).