Automated description from the Alliance of Genome Resources
Exhibits histone demethylase activity (H3-K4 specific). Involved in several processes, including animal organ morphogenesis; cellular response to leukemia inhibitory factor; and regulation of gene expression. Predicted to localize to the cytosol and histone methyltransferase complex. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability; breast cancer; and malignant glioma. Orthologous to human KDM5B (lysine demethylase 5B).