Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits 1-phosphatidylinositol-3-kinase activity and insulin receptor substrate binding activity. Involved in several processes, including angiogenesis involved in wound healing; embryonic cleavage; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to localize to several cellular components, including brush border membrane; midbody; and nuclear lumen. Is expressed in several structures, including early embryo; face; genitourinary system; respiratory system; and spleen. Human ortholog(s) of this gene implicated in glioblastoma multiforme; prostate adenocarcinoma; prostate cancer; and type 2 diabetes mellitus. Orthologous to human PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta).