Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable calcium channel activity and ribosome binding activity. Involved in calcium ion transmembrane transport and endoplasmic reticulum calcium ion homeostasis. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of multi-pass translocon complex. Predicted to be active in endoplasmic reticulum. Is expressed in clavicle; mandible; maxilla; and rib. Used to study craniofacial dysmorphism, skeletal anomalies, and mental retardation syndrome. Human ortholog(s) of this gene implicated in craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome 1. Orthologous to human TMCO1 (transmembrane and coiled-coil domains 1).