Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable 1-phosphatidylinositol binding activity; ATPase binding activity; and phosphatidylinositol phosphate binding activity. Involved in osteoclast differentiation. Acts upstream of or within several processes, including bone mineralization involved in bone maturation; bone resorption; and cellular response to leukemia inhibitory factor. Located in several cellular components, including apical cytoplasm; endoplasmic reticulum; and secretory granule. Is expressed in chondrocranium; incisor; limb; and nose. Used to study autosomal recessive osteopetrosis 8. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 8. Orthologous to human SNX10 (sorting nexin 10).