Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and transcription corepressor activity. Predicted to contribute to ubiquitin-protein transferase activity. Involved in blastocyst hatching and negative regulation of transcription by RNA polymerase II. Localizes to nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; gonad; and lung. Human ortholog(s) of this gene implicated in syndromic microphthalmia 1 and syndromic microphthalmia 2. Orthologous to human BCOR (BCL6 corepressor).