Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables K48-linked polyubiquitin modification-dependent protein binding activity and ubiquitin binding activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process; protein targeting to ER; and regulation of insulin-like growth factor receptor signaling pathway. Located in endoplasmic reticulum and membrane. Part of proteasome complex. Orthologous to human ZFAND2B (zinc finger AN1-type containing 2B).