Automated description from the Alliance of Genome Resources (Release 4.1.0)
Enables ATP binding activity; calcium activated cation channel activity; and calcium channel activity. Involved in several processes, including cellular response to ATP; dendritic cell chemotaxis; and protein homotetramerization. Acts upstream of or within calcium ion transport. Located in plasma membrane. Is spanning component of plasma membrane. Is expressed in brain; cochlea; dorsal root ganglion; inferior vagus ganglion; and vagus ganglion. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis et progressiva 6 and progressive familial heart block type IB. Orthologous to human TRPM4 (transient receptor potential cation channel subfamily M member 4).