Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits ATP binding activity; calcium activated cation channel activity; and calcium channel activity. Involved in several processes, including cation transport; cellular response to ATP; and protein homotetramerization. Localizes to spanning component of plasma membrane. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis and progressive familial heart block type IB. Is expressed in brain; cochlea; dorsal root ganglion; inferior vagus ganglion; and vagus ganglion. Orthologous to human TRPM4 (transient receptor potential cation channel subfamily M member 4).