Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable methenyltetrahydrofolate cyclohydrolase activity; methylenetetrahydrofolate dehydrogenase (NAD+) activity; and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in 10-formyltetrahydrofolate metabolic process and tetrahydrofolate interconversion. Predicted to act upstream of or within amino acid biosynthetic process; one-carbon metabolic process; and purine nucleotide biosynthetic process. Predicted to be located in mitochondrial inner membrane and mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in several structures, including central nervous system; future brain; gonad; gut; and retina nuclear layer. Orthologous to human MTHFD2L (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like).