Automated description from the Alliance of Genome Resources
Predicted to have several functions, including identical protein binding activity; transforming growth factor beta receptor binding activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; positive regulation of trophoblast cell migration; and ubiquitin-dependent protein catabolic process. Predicted to localize to the cytoplasm; nuclear speck; and ubiquitin ligase complex. Used to study diffuse large B-cell lymphoma. Is expressed in cardiovascular system; eye; genitourinary system; gut; and lung. Orthologous to human SMURF2 (SMAD specific E3 ubiquitin protein ligase 2).