Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables phosphoprotein binding activity and protein kinase binding activity. Involved in several processes, including establishment of skin barrier; protein kinase A signaling; and regulation of epidermal cell division. Acts upstream of or within keratinocyte differentiation; negative regulation of cell population proliferation; and regulation of cell cycle. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in transitional cell carcinoma and vulva squamous cell carcinoma. Orthologous to human SFN (stratifin).