Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable axon guidance receptor activity and identical protein binding activity. Involved in several processes, including circulatory system development; neuron development; and positive regulation of Notch signaling pathway. Acts upstream of or within axon guidance and metanephros development. Located in axolemma. Is expressed in several structures, including autopod; central nervous system; embryo mesenchyme; jaw; and urinary system. Human ortholog(s) of this gene implicated in vesicoureteral reflux. Orthologous to human ROBO2 (roundabout guidance receptor 2).