Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including glandular epithelial cell differentiation; negative regulation of epithelial cell apoptotic process; and parathyroid gland development. Located in nucleus. Is expressed in several structures, including branchial pouch; central nervous system; foregut gland primordium; genitourinary system; and gut gland. Used to study hypoparathyroidism. Human ortholog(s) of this gene implicated in familial isolated hypoparathyroidism and hyperparathyroidism. Orthologous to human GCM2 (glial cells missing transcription factor 2).