Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables protein serine/threonine kinase activity. Involved in several processes, including cellular hypotonic response; intracellular chloride ion homeostasis; and negative regulation of transport. Acts upstream of or within monoatomic ion homeostasis; regulation of blood pressure; and regulation of inflammatory response. Located in basolateral plasma membrane. Is active in apical plasma membrane and cell body. Is expressed in brain and metanephros. Used to study Gitelman syndrome and pseudohypoaldosteronism. Orthologous to human STK39 (serine/threonine kinase 39).