Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable G protein-coupled receptor activity and calcium ion binding activity. Involved in Wnt signaling pathway, planar cell polarity pathway; dopaminergic neuron axon guidance; and serotonergic neuron axon guidance. Acts upstream of or within several processes, including cilium assembly; generation of neurons; and regulation of protein phosphorylation. Predicted to be located in plasma membrane. Is expressed in several structures, including central nervous system; embryo ectoderm; epiblast; peripheral nervous system; and retina. Orthologous to human CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3).