Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables several functions, including SH3 domain binding activity; clathrin binding activity; and protein dimerization activity. Involved in several processes, including negative regulation of supramolecular fiber organization; positive regulation of clathrin coat assembly; and regulation of gastric acid secretion. Acts upstream of or within receptor-mediated endocytosis. Located in several cellular components, including apical plasma membrane; clathrin-coated pit; and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; bone; central nervous system; genitourinary system; and sensory organ. Orthologous to human HIP1R (huntingtin interacting protein 1 related).