GO Annotations Graph

• Symbol: Hip1r
• Name: huntingtin interacting protein 1 related
• ID: MGI:1352504

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IDA	J:59125
Molecular Function	GO:0051015	actin filament binding	ISO	J:164563
Molecular Function	GO:0051015	actin filament binding	IDA	J:236220
Molecular Function	GO:0051015	actin filament binding	IDA	J:236215
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0035615	clathrin adaptor activity	IC	J:236215
Molecular Function	GO:0035615	clathrin adaptor activity	IDA	J:236220
Molecular Function	GO:0035615	clathrin adaptor activity	IBA	J:265628
Molecular Function	GO:0030276	clathrin binding	ISO	J:164563
Molecular Function	GO:0030276	clathrin binding	IDA	J:236220
Molecular Function	GO:0032051	clathrin light chain binding	IPI	J:230636
Molecular Function	GO:0032051	clathrin light chain binding	IPI	J:236215
Molecular Function	GO:0032051	clathrin light chain binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0035091	phosphatidylinositol binding	ISO	J:164563
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	ISO	J:164563
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	IBA	J:265628
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	IBA	J:265628
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0005543	phospholipid binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:236216
Molecular Function	GO:0005515	protein binding	IPI	J:322386
Molecular Function	GO:0005515	protein binding	IPI	J:200317
Molecular Function	GO:0005515	protein binding	IPI	J:236216
Molecular Function	GO:0046982	protein heterodimerization activity	IPI	J:230636
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:236220
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:236215
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:230636
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0017124	SH3 domain binding	IDA	J:236216
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:137705
Cellular Component	GO:0005938	cell cortex	IDA	J:236220
Cellular Component	GO:0005905	clathrin-coated pit	IDA	J:236220
Cellular Component	GO:0005905	clathrin-coated pit	IDA	J:59125
Cellular Component	GO:0030136	clathrin-coated vesicle	ISO	J:164563
Cellular Component	GO:0030136	clathrin-coated vesicle	IDA	J:59125
Cellular Component	GO:0030136	clathrin-coated vesicle	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IDA	J:59125
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0032839	dendrite cytoplasm	ISS	J:236218
Cellular Component	GO:0043197	dendritic spine	ISS	J:236218
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISS	J:236218
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:59125
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	ISS	J:236218
Cellular Component	GO:0032587	ruffle membrane	ISO	J:164563
Cellular Component	GO:0097060	synaptic membrane	ISS	J:236218
Biological Process	GO:0007015	actin filament organization	IBA	J:265628
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IEA	J:72247
Biological Process	GO:0048268	clathrin coat assembly	IDA	J:236220
Biological Process	GO:0048268	clathrin coat assembly	IBA	J:265628
Biological Process	GO:0055123	digestive system development	IMP	J:137705
Biological Process	GO:0006897	endocytosis	IBA	J:265628
Biological Process	GO:0061024	membrane organization	IMP	J:137705
Biological Process	GO:0030837	negative regulation of actin filament polymerization	IDA	J:236216
Biological Process	GO:0030837	negative regulation of actin filament polymerization	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:137705
Biological Process	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation	IDA	J:236216
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:1905445	positive regulation of clathrin coat assembly	IDA	J:230636
Biological Process	GO:2000370	positive regulation of clathrin-dependent endocytosis	IC	J:236220
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:2000588	positive regulation of platelet-derived growth factor receptor-beta signaling pathway	ISO	J:164563
Biological Process	GO:0032092	positive regulation of protein binding	ISO	J:164563
Biological Process	GO:0099173	postsynapse organization	ISO	J:155856
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0006898	receptor-mediated endocytosis	ISO	J:164563
Biological Process	GO:0006898	receptor-mediated endocytosis	IDA	J:59125
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	IGI	J:236217
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:2000369	regulation of clathrin-dependent endocytosis	NAS	J:236216
Biological Process	GO:0030100	regulation of endocytosis	ISO	J:164563
Biological Process	GO:0060453	regulation of gastric acid secretion	IMP	J:137705