Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have ubiquitin-protein transferase activity. Involved in negative regulation of transcription, DNA-templated; positive regulation of actin nucleation; and regulation of circadian rhythm. Localizes to cytoplasm and nucleus. Predicted to colocalize with retromer complex. Is expressed in several structures, including brain; egg cylinder; reproductive system; turbinate bone primordium; and vertebral axis musculature. Used to study Prader-Willi syndrome. Human ortholog(s) of this gene implicated in Schaaf-Yang syndrome. Orthologous to human MAGEL2 (MAGE family member L2).