Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits group III metabotropic glutamate receptor activity. Predicted to be involved in several processes, including detection of mechanical stimulus involved in sensory perception of pain; glutamatergic synaptic transmission; and modulation of chemical synaptic transmission. Predicted to localize to several cellular components, including GABA-ergic synapse; glutamatergic synapse; and integral component of presynaptic active zone membrane. Is expressed in several structures, including eye; gonad; ileum; liver and biliary system; and nervous system. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autistic disorder; and schizophrenia. Orthologous to human GRM8 (glutamate metabotropic receptor 8).