Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific; promoter-specific chromatin binding activity; and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; positive regulation of angiogenesis; and vasculature development. Predicted to localize to nuclear body. Is expressed in several structures, including cardiovascular system; central nervous system; embryo mesenchyme; limb long bone; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including lymphedema; lymphedema-distichiasis syndrome; obesity; ptosis; and type 2 diabetes mellitus. Orthologous to human FOXC2 (forkhead box C2).