About   Help   FAQ
Gene Ontology Classifications
forkhead box G1

Go Annotations as Summary Text (Tabular View) (GO Graph)

GO curators for mouse genes have assigned the following annotations to the gene product of Foxg1. (This text reflects annotations as of Tuesday, May 26, 2015.)
Summary from NCBI RefSeq

[Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes a member of the forked-head transcription factor family. The encoded protein, which functions as a repressor, may play a role in brain development. Mutations at this locus have been associated with Rett syndrome. [provided by RefSeq, Feb 2012]
Summary text based on GO annotations supported by experimental evidence in mouse
Summary text based on GO annotations supported by experimental evidence in other organisms
Summary text based on GO annotations supported by structural data
Summary text for additional MGI annotations
  1. Choi PS et al. (2008) Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron, 57:41-55. (PubMed:18184563)
  2. Hanashima C et al. (2004) Foxg1 suppresses early cortical cell fate. Science, 303:56-9. (PubMed:14704420)
  3. Hanashima C et al. (2002) Brain factor-1 controls the proliferation and differentiation of neocortical progenitor cells through independent mechanisms. J Neurosci, 22:6526-36. (PubMed:12151532)
  4. Marcal N et al. (2005) Antagonistic effects of Grg6 and Groucho/TLE on the transcription repression activity of brain factor 1/FoxG1 and cortical neuron differentiation. Mol Cell Biol, 25:10916-29. (PubMed:16314515)
  5. Martynoga B et al. (2005) Foxg1 is required for specification of ventral telencephalon and region-specific regulation of dorsal telencephalic precursor proliferation and apoptosis. Dev Biol, 283:113-27. (PubMed:15893304)
  6. Miyoshi G et al. (2012) Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate. Neuron, 74:1045-58. (PubMed:22726835)
  7. Pauley S et al. (2006) Foxg1 is required for morphogenesis and histogenesis of the mammalian inner ear. Dev Dyn, 235:2470-2482. (PubMed:16691564)
  8. Pratt T et al. (2004) The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse. Development, 131:3773-84. (PubMed:15240555)
  9. Shen Q et al. (2006) The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells. Nat Neurosci, 9:743-51. (PubMed:16680166)
  10. Shibata M et al. (2008) MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium. J Neurosci, 28:10415-21. (PubMed:18842901)
  11. Vyas A et al. (2003) Paleocortex is specified in mice in which dorsal telencephalic patterning is severely disrupted. J Comp Neurol, 466:545-53. (PubMed:14566948)
  12. Xuan S et al. (1995) Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Neuron, 14:1141-52. (PubMed:7605629)
  13. Yip DJ et al. (2012) Snf2l regulates Foxg1-dependent progenitor cell expansion in the developing brain. Dev Cell, 22:871-8. (PubMed:22516202)

Go Annotations in Tabular Form (Text View) (GO Graph)

Filter Markers by: Category  Evidence Code 


Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral sequence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISS Inferred from sequence or structural similarity
  ISO Inferred from sequence orthology
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  NAS Non-traceable author statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.0
The Jackson Laboratory