Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables MAP kinase kinase activity and molecular adaptor activity. Involved in several processes, including MAPK cascade; nervous system development; and transmembrane receptor protein tyrosine kinase signaling pathway. Acts upstream of or within several processes, including ERK1 and ERK2 cascade; regulation of neuron projection development; and respiratory system development. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in cardiofaciocutaneous syndrome 4 and small intestine adenocarcinoma. Orthologous to human MAP2K2 (mitogen-activated protein kinase kinase 2).