Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including nuclear receptor binding activity; peroxisome proliferator activated receptor binding activity; and protein homodimerization activity. Involved in circadian regulation of gene expression and negative regulation of DNA-templated transcription. Acts upstream of or within Notch signaling pathway. Predicted to be located in nucleoplasm. Predicted to be part of chromatin. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including adrenal medulla; gut; nervous system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human NR0B2 (nuclear receptor subfamily 0 group B member 2).