Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables enzyme binding activity; transcription corepressor activity; and ubiquitin-protein transferase regulator activity. Involved in several processes, including cellular response to insulin stimulus; negative regulation of fat cell differentiation; and negative regulation of fatty acid biosynthetic process. Acts upstream of or within negative regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including bone; central nervous system; genitourinary system; heart; and retina. Orthologous to human TRIB3 (tribbles pseudokinase 3).