Automated description from the Alliance of Genome Resources
Exhibits LRR domain binding activity; protein kinase activator activity; and protein serine/threonine kinase activity. Involved in several processes, including generation of neurons; positive regulation of protein phosphorylation; and regulation of signal transduction. Localizes to several cellular components, including the TCR signalosome; cytosol; and nucleus. Used to study Peutz-Jeghers syndrome and endometrial cancer. Human ortholog(s) of this gene implicated in Peutz-Jeghers syndrome; cervical mucinous adenocarcinoma; ovarian carcinoma; and pancreatic cancer. Is expressed in several structures, including alimentary system; blood; genitourinary system; lung; and nervous system. Orthologous to human STK11 (serine/threonine kinase 11).