Automated description from the Alliance of Genome Resources
Exhibits NAD+ ADP-ribosyltransferase activity; chromatin binding activity; and protein ADP-ribosylase activity. Involved in several processes, including DNA metabolic process; mitochondrion organization; and regulation of DNA metabolic process. Localizes to the cytoplasm; nucleus; and protein-containing complex. Human ortholog(s) of this gene implicated in several diseases, including arthritis; asthma; bacterial meningitis; neurodegenerative disease (multiple); and stomach carcinoma. Orthologous to human PARP1 (poly(ADP-ribose) polymerase 1).