Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables kinase activator activity. Involved in synaptic vesicle endocytosis. Acts upstream of or within negative regulation of neuron apoptotic process; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and small GTPase-mediated signal transduction. Located in clathrin-coated pit; endocytic vesicle; and lamellipodium. Is active in calyx of Held and presynaptic endocytic zone. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skeleton. Orthologous to human ITSN1 (intersectin 1).