Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits chromatin binding activity; sequence-specific DNA binding activity; and transcription corepressor activity. Involved in several processes, including animal organ development; negative regulation of fat cell differentiation; and positive regulation of protein deacetylation. Localizes to histone deacetylase complex and nuclear body. Is expressed in several structures, including branchial arch; central nervous system; limb; retina layer; and tooth. Used to study myelofibrosis. Human ortholog(s) of this gene implicated in osteoarthritis. Orthologous to human NCOR2 (nuclear receptor corepressor 2).