Automated description from the Alliance of Genome Resources
Exhibits ferrous iron transmembrane transporter activity; identical protein binding activity; and peptide hormone binding activity. Involved in several processes, including iron ion export across plasma membrane; multicellular organismal iron ion homeostasis; and regulation of transcription by RNA polymerase II. Localizes to the basolateral plasma membrane and synaptic vesicle. Used to study hemochromatosis type 4. Human ortholog(s) of this gene implicated in hemochromatosis type 4. Is expressed in several structures, including central nervous system; extraembryonic component; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human SLC40A1 (solute carrier family 40 member 1).