Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits ferrous iron transmembrane transporter activity; identical protein binding activity; and peptide hormone binding activity. Involved in several processes, including iron ion export across plasma membrane; multicellular organismal iron ion homeostasis; and regulation of transcription by RNA polymerase II. Localizes to basolateral plasma membrane and synaptic vesicle. Is expressed in several structures, including central nervous system; extraembryonic component; genitourinary system; gut; and hemolymphoid system gland. Used to study hemochromatosis type 4. Human ortholog(s) of this gene implicated in hemochromatosis type 4. Orthologous to human SLC40A1 (solute carrier family 40 member 1).