Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits cysteine-type endopeptidase activator activity involved in apoptotic process and identical protein binding activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; nervous system development; and regulation of apoptotic process. Localizes to cytosol and nucleus. Is expressed in several structures, including heart; inner cell mass; limb interdigital region; liver; and vibrissa. Used to study Noonan syndrome. Orthologous to human APAF1 (apoptotic peptidase activating factor 1).