Automated description from the Alliance of Genome Resources
Exhibits Wnt-protein binding activity; apolipoprotein binding activity; and toxin transmembrane transporter activity. Involved in several processes, including animal organ development; embryonic morphogenesis; and negative regulation of non-canonical Wnt signaling pathway. Localizes to the early endosome and plasma membrane. Predicted to colocalize with the Golgi apparatus. Used to study fatty liver disease and neural tube defect. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human LRP6 (LDL receptor related protein 6).