Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits several functions, including chromatin binding activity; transcription coactivator activity; and transcription factor binding activity. Involved in several processes, including cellular response to Thyroglobulin triiodothyronine; labyrinthine layer morphogenesis; and positive regulation of transcription from RNA polymerase II promoter by galactose. Predicted to localize to several cellular components, including cytosol; neuron projection; and nuclear lumen. Is expressed in several structures, including brain; dorsal grey horn; early conceptus; genitourinary system; and retina. Used to study obesity and thyroid hormone resistance syndrome. Orthologous to human NCOA1 (nuclear receptor coactivator 1).